วันพฤหัสบดีที่ 24 ตุลาคม พ.ศ. 2556

Disadvantage of NIR spectroscopy

"Like other techniques, NIR spectroscopy has also some drawbacks. The low sensitivity of this technique restricts the determination of the active principles with less than 0.01% (w/w). NIR spectroscopy is an indirect method which requires a reference method, Chemometric techniques - statistical and mathematical procedures - to extract, and interpret spectral information acquired from the sample NIR spectra"

(FT-NIR spectroscopy and Laser Diffraction particle sizing of APIs in Pharmaceutical formulations
Joana Lucia Carrilho Figuriredo, Mestrado Integrado em Engenharia Quimica, Setembro de 2008)
(Celio Pasquini (2003) Near Infrared Spectroscopy: Fundamentals, Practical Aspects and Analytical Applications: J. Braz. Chem. Soc.; Vol. 14 No. 2)

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